Type 2 Diabetes
Diabetic patients will develop severe vascular inflammatory changes leading to a number of complications if not adequately controlled.
T2D is an inflammatory progressive disease involving insulin producing β-cells in the pancreas and all arteries in the body. T2D can be a “silent" disease for many years without notable symptoms and is often revealed by chance. T2D is characterized by persistently high blood glucose concentrations. If not adequately controlled, T2D patients will develop severe vascular inflammatory changes leading to a number of complications including stroke, blindness, amputation, kidney failure and heart attack. Each of these complications is a debilitating burden to the patient and a huge health economic burden to the society. A careful diagnosis, control of blood glucose and medical treatment is of importance.
SER140 focuses on treating the progression of T2D, by prolonging normal β-cell function and by increasing insulin production. Furthermore, SER140 will improve insulin receptor sensitivity. All of these effects are related to the anti-inflammatory effect of SER140.